Physiologically-based pharmacokinetic model predictions of inter-ethnic differences in imatinib pharmacokinetics and dosing regimens
Aims: This study implements a physiologically-based pharmacokinetic (PBPK) modelling approach to investigate inter-ethnic differences in imatinib pharmacokinetics and dosing regimens. Methods: A PBPK model of imatinib was built in the Simcyp Simulator (version 17) integrating in vitro drug metabolis...
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| Format: | Article |
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John Wiley and Sons Inc
2022
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