Preparation and Cytotoxic Evaluation of PGV-1 Derivative, CCA-1.1, as a New Curcumin Analog with Improved-Physicochemical and Pharmacological Properties

Purpose: This study aimed to challenge the anticancer potency of pentagamavunone-1 (PGV- 1) and obtain a new compound (Chemoprevention-Curcumin Analog 1.1, CCA-1.1) with improved chemical and pharmacological properties. Methods: CCA-1.1 was prepared by changing the ketone group of PGV-1 into a hydro...

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Main Authors: Utomo, Rohmad Yudi, Wulandari, Febri, Novitasari, Dhania, Lestari, Beni, Susidarti, Ratna Asmah, Jenie, Riris Istighfari, Kato, Jun-Ya, Sardjiman, Sardjiman, Meiyanto, Edy
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2022
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Online Access:https://repository.ugm.ac.id/282848/1/Preparation%20and%20Cytotoxic%20Evaluation%20of%20PGV-1%20Derivative%2C%20CCA-1.1%2C%20as%20a%20New%20Curcumin%20Analog%20with%20Improved-Physicochemical%20and%20Pharmacological%20Properties.pdf