Pharmacophore-guided Virtual Screening to Identify New β3-adrenergic Receptor Agonists

Pharmacophore-guided Virtual Screening to Identify New β3-adrenergic Receptor Agonists

The β3-adrenergic receptor (β3-AR) is found in several tissues such as adipose tissue and urinary bladder. It is a therapeutic target because it plays a role in thermogenesis, lipolysis, and bladder relaxation. Two β3-AR agonists are used clinically: mirabegron 1 and vibegron 2, which are indicated...

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Bibliographic Details
Main Authors: Ujiantari, Navista Sri Octa, Ham, Seungmin, Nagiri, Chisae, Shihoya, Wataru, Nureki, Osamu, Hutchinson, Dana Sabine, Schuster, Daniela
Format: Article
Language:English
Published: John Wiley and Sons Inc 2022
Subjects:
Pharmaceutical Sciences
Online Access:https://repository.ugm.ac.id/283359/1/55_Pharmacophore-guided%20Virtual%20Screening%20to%20Identify%20New%20%CE%B23-adrenergic%20Receptor%20Agonists.pdf

Internet

https://repository.ugm.ac.id/283359/1/55_Pharmacophore-guided%20Virtual%20Screening%20to%20Identify%20New%20%CE%B23-adrenergic%20Receptor%20Agonists.pdf

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