Pharmacophore-guided Virtual Screening to Identify New β3-adrenergic Receptor Agonists
The β3-adrenergic receptor (β3-AR) is found in several tissues such as adipose tissue and urinary bladder. It is a therapeutic target because it plays a role in thermogenesis, lipolysis, and bladder relaxation. Two β3-AR agonists are used clinically: mirabegron 1 and vibegron 2, which are indicated...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
John Wiley and Sons Inc
2022
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| Subjects: | |
| Online Access: | https://repository.ugm.ac.id/283359/1/55_Pharmacophore-guided%20Virtual%20Screening%20to%20Identify%20New%20%CE%B23-adrenergic%20Receptor%20Agonists.pdf |