Validation of RP-HPLC method for determination of pH-dependent solubility of ketoconazole in phosphate buffer pH 6.8
The solubility of ketoconazole is highly dependent on the pH of the medium. Solubility is an important physicochemical parameter needed to consider and predict to obtain the drug behavior in a physiological environment. Determination of solubility of ketoconazole in pH of intestine fluid (6-7.4) is...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Marmara University
2022
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| Subjects: | |
| Online Access: | https://repository.ugm.ac.id/283679/1/Validation%20of%20RP-HPLC%20method%20for%20determination%20of%20pH-.pdf |