Synthesis, Cytotoxicity Evaluation and Molecular Docking Studies of Xanthyl-Cinnamate Derivatives as Potential Anticancer Agents

A new series of xanthyl-cinnamate hybrid compounds (4a-d) have been synthesized and screened through in vitro assay against four human cancer cell lines, i.e., HeLa, T47D, A549, and WiDr. The results revealed that xanthone hybridization with cinnamic acid increases the selectivity of the compound...

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Bibliographic Details
Main Authors: Iresha, Muthia Rahayu, Jumina, Jumina, Pranowo, Harno Dwi, Sholikhah, Eti Nurwening, Hermawan, Faris
Format: Other
Language:English
Published: Indonesian Journal of Chemistry 2022
Subjects:
Online Access:https://repository.ugm.ac.id/284140/1/Synthesis-Cytotoxicity-Evaluation-and-Molecular-Docking-Studies-of-XanthylCinnamate-Derivatives-as-Potential-Anticancer-AgentsIndonesian-Journal-of-Chemistry.pdf