Microencapsulation of alpha-mangostin into PLGA microspheres and optimization using response surface methodology intended for pulmonary delivery
Documented to exhibit cytotoxicity and poor oral bioavailability, alpha-mangostin was encapsulated into PLGA microspheres with optimization of formulation using response surface methodology. Mixed levels of four factors Face central composite design was employed to evaluate critical formulation vari...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Informa Healthcare
2013
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/31882/1/Microencapsulation_of_alpha_mangostin_J_Micro.pdf |