Genetic Polymorphism of CYP2D6 and MDR1 in breast cancer patients treated with tamoxifen

Introduction: Tamoxifen is the drug of choice for the treatment of breast cancer patients who are positive for estrogen receptor. It is metabolized by Cytochrome P450 2D6 (CYP2D6) and the variations in CYP2D6 activity has been reported to have important therapeutic consequences which include develop...

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Bibliographic Details
Main Authors: Mohamad, NI, Ismail, S, Hamzah , S, Harun, R, Ngow , Harris Abdullah
Format: Proceeding Paper
Language:English
Published: 2010
Subjects:
Online Access:http://irep.iium.edu.my/5238/1/Abstract_CYP2D6_NNCC.pdf