Development of novel isolation methodologies for microvesicles and exosomes, as potential biomarkers for health (Therapeutic Lifestyle Changes), and use of microvesicle-delivered β-Gly in erythroleukaemia
Both MVs and exosomes are isolated by similar methodologies such as differential centrifugation of cell culture supernatant (S/N), filtration, floating on chemical gradients or using antibody labelled magnetic beads. Hence, the isolation techniques, commonly in use, provide low levels of purificatio...
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| Format: | Thesis |
| Language: | English |
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2016
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| Online Access: | https://repository.londonmet.ac.uk/1350/1/RyanGrant_PhD_Final.pdf |