Phosphorylation of protein kinase B, the key enzyme in insulin signalling cascade, is enhanced in linoleic and arachidonic acid treated HT29 and HepG2 cells
Objective: Defects in insulin signalling pathway have been implicated in the pathogenesis of impaired glucose uptake, insulin resistance and type II diabetes. However, the specific defects that precipitate these abnormalities are yet to be fully elucidated. The plasma membrane embedded insulin recep...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2018
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| Subjects: | |
| Online Access: | https://repository.londonmet.ac.uk/1468/2/Accepted%20%20manuscript%2014_05_18.pdf |