Peptidylarginine deiminases post-translationally deiminate prohibitin and modulate extracellular vesicle release and microRNAs in glioblastoma multiforme

Glioblastoma multiforme (GBM) is the most aggressive form of adult primary malignant brain tumour with poor prognosis. Extracellular vesicles (EVs) are a key-mediator through which GBM cells promote a pro-oncogenic microenvironment. Peptidylarginine deiminases (PADs), which catalyze the post-transla...

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Bibliographic Details
Main Authors: Kosgodage, Uchini S., Uysal-Onganer, Pinar, MacLatchy, Amy, Kraev, Igor, Chatterton, Nicholas P., Nicholas, Anthony P., Inal, Jameel, Lange, Sigrun
Format: Article
Language:English
Published: MDPI 2018
Subjects:
Online Access:https://repository.londonmet.ac.uk/4577/1/article.pdf