Peptidylarginine deiminases post-translationally deiminate prohibitin and modulate extracellular vesicle release and microRNAs in glioblastoma multiforme
Glioblastoma multiforme (GBM) is the most aggressive form of adult primary malignant brain tumour with poor prognosis. Extracellular vesicles (EVs) are a key-mediator through which GBM cells promote a pro-oncogenic microenvironment. Peptidylarginine deiminases (PADs), which catalyze the post-transla...
Main Authors: | Kosgodage, Uchini S., Uysal-Onganer, Pinar, MacLatchy, Amy, Kraev, Igor, Chatterton, Nicholas P., Nicholas, Anthony P., Inal, Jameel, Lange, Sigrun |
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Format: | Article |
Language: | English |
Published: |
MDPI
2018
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Subjects: | |
Online Access: | https://repository.londonmet.ac.uk/4577/1/article.pdf |
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