Elucidating the role of Mitoferrin (Mfrn), Iron Regulatory Proteins (IRP1 and IRP2) and Hephaestin (Heph) in Iron Metabolism by tagSNP and Protein-Protein Interaction (PPI) analysis

Precisely how Hephaestin (Heph) facilitate iron release from cells is poorly understood. The work in this thesis tried to establish the role of different iron metabolic proteins, Mitoferrin (Mfrn), IRPs and Heph in iron homeostasis. Analysis of 18 tagSNPs in the Mfrn gene was carried out in an Asian...

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Bibliographic Details
Main Author: Velaga, Ravindrath M.
Format: Thesis
Language:English
Published: 2014
Subjects:
Online Access:https://repository.londonmet.ac.uk/4597/1/R%20Velaga%20PhD%20thesis%20-%20After%20Corrections-%20070714.pdf