A preliminary investigation of additive manufacture to fabricate human nail plate surrogates for pharmaceutical testing

In vitro permeation studies using nail clippings or nail plates are commonly used in the development of transungual formulations. However, there are ethical, safety and cost issues associated with sourcing such tissues. Herein, we describe a preliminary approach is described for the design and manuf...

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Bibliographic Details
Main Authors: Sil dos Santos, Bruno, Patel, Avnish, Crowther, Jonathan M., Moore, David J., Hadgraft, Jonathan, Hilton, Stephen T., Lane, Majella E.
Format: Article
Language:English
Published: MDPI 2019
Subjects:
Online Access:https://repository.londonmet.ac.uk/4912/1/pharmaceutics-11-00250.pdf