Peptidylarginine deiminase inhibitors reduce bacterial membrane vesicle release and sensitize bacteria to antibiotic treatment

Outer membrane and membrane vesicles (OMV/MV) are released from bacteria and participate in cell communication, biofilm formation and host-pathogen interactions. Peptidylarginine deiminases (PADs) are phylogenetically conserved enzymes that catalyze post-translational deimination/citrullination of p...

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Bibliographic Details
Main Authors: Kosgodage, Uchini S., Matewele, Paul, Mastroianni, Giulia, Kraev, Igor, Brotherton, Dominik, Awamaria, Brigitte, Nicholas, Anthony P., Lange, Sigrun, Inal, Jameel
Format: Article
Language:English
Published: Frontiers Media S.A. 2019
Subjects:
Online Access:https://repository.londonmet.ac.uk/4974/1/fcimb-09-00227.pdf