Recent advances in understanding mammalian prion structure: a mini review
Prions are lethal pathogens, which cause fatal neurodegenerative diseases in mammals. They are unique infectious agents and are composed of self-propagating multi-chain assemblies of misfolded host-encoded prion protein (PrP). Understanding prion structure is fundamental to understanding prion disea...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media
2019
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Subjects: | |
Online Access: | https://repository.londonmet.ac.uk/5046/1/fnmol-12-00169.pdf |