Recent advances in understanding mammalian prion structure: a mini review

Prions are lethal pathogens, which cause fatal neurodegenerative diseases in mammals. They are unique infectious agents and are composed of self-propagating multi-chain assemblies of misfolded host-encoded prion protein (PrP). Understanding prion structure is fundamental to understanding prion disea...

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Bibliographic Details
Main Authors: Terry, Cassandra, Wadsworth, Jonathan D. F.
Format: Article
Language:English
Published: Frontiers Media 2019
Subjects:
Online Access:https://repository.londonmet.ac.uk/5046/1/fnmol-12-00169.pdf