Leishmania aethiopica cell-to-cell spreading involves caspase-3, AkT and NF-κB but not PKC-δ activation and involves uptake of LAMP-1 positive bodies containing parasites
Development of human leishmaniasis is dependent on the ability of intracellular Leishmania parasites to spread and enter macrophages. The mechanism through which free promastigotes and amastigotes, bind and enter host macrophages has been previously investigated, however little is known about intrac...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2020
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| Subjects: | |
| Online Access: | https://repository.londonmet.ac.uk/5395/1/10.1111%40febs.15166.pdf |