Fabricating a novel HLC-hBMP2 fusion protein for the treatment of bone defects

Treating serious bone trauma with an osteo-inductive agent such as bone morphogenetic proteins (BMPs) has been considered as an optimized option when delivered via a collagen sponge (CS). Previous work has shown that the BMP concentration and release rate from approved CS carriers is difficult to co...

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Bibliographic Details
Main Authors: Chen, Zhuoyue, Zhang, Zhen, Wang, Zhaoyue, Wu, Jiawei, Wang, Yihang, Si, He, Xie, Xin, Shang, Lijun, Fan, Daidi, Chen, Fulin
Format: Article
Language:English
Published: Elsevier 2020
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Online Access:https://repository.londonmet.ac.uk/6199/1/Manuscript-Clear-Final-SHANG.pdf