IgA binds to the AD-2 epitope of glycoprotein B and neutralizes human cytomegalovirus

Human cytomegalovirus (HCMV) is a ubiquitous pathogen that is potentially pathogenic in immunosuppressed individuals and pregnant females during primary infection. The HCMV envelope glycoprotein B (gB) facilitates viral entry into all cell types and induces a potent immune response. AD-2 epitope is...

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Bibliographic Details
Main Authors: Siddiqui, Saima, Hackl, Sarah, Ghoddusi, Hamid, McIntosh, Megan, Gomes, Ariane, Ho, Joshua, Reeves, Matthew B., McLean, Gary R.
Format: Article
Language:English
Published: Wiley 2020
Subjects:
Online Access:https://repository.londonmet.ac.uk/6240/1/Immunology_2020.pdf