Cascading classifier application for topology prediction of transmembrane beta-barrel proteins

Membrane proteins are a major focus for new drug discovery. Transmembrane beta-barrel proteins play key roles in the translocation machinery, pore formation, membrane anchoring and ion exchange. Given their key roles and the difficulty in membrane protein structure determination, the use of computat...

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Bibliographic Details
Main Authors: Kazemian, Hassan, Grimaldi, Cédric Maxime
Format: Article
Language:English
Published: Imperial College Press 2020
Subjects:
Online Access:https://repository.londonmet.ac.uk/6280/1/JBCB-1097_R2%282%29-submitted.pdf