A preliminary investigation into the use of amino acids as potential ion pairs for diclofenac transdermal delivery

Ion pairing is a potential strategy used to increase the partition and permeation of ionisable drug molecules. This work outlines the process of identifying, selecting and testing potential counter ions for diclofenac (DF). Three screening criteria were considered in the initial selection process. T...

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Bibliographic Details
Main Authors: Cristofoli, Mignon, Hadgraft, Jonathan, Lane, Majella E., Sil dos Santos, Bruno
Format: Article
Language:English
Published: Elsevier 2022
Subjects:
Online Access:https://repository.londonmet.ac.uk/7781/1/1-s2.0-S0378517322004616-main.pdf