A pilot study on peptidylarginine deiminases and protein deimination in animal cancers across vertebrate species

PADs are a group of calcium-dependent enzymes that play key roles in inflammatory pathologies and have diverse roles in cancers. PADs cause irreversible post-translational modification of arginine to citrulline, leading to changes in protein function in different cellular compartments. PAD isozyme d...

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Bibliographic Details
Main Authors: Inal, Jameel, Hristova, Mariya, Lange, Sigrun
Format: Article
Language:English
Published: MDPI 2022
Subjects:
Online Access:https://repository.londonmet.ac.uk/7848/1/ijms-23-08697-v2.pdf