Molecular basis of selectivity and activity for the antimicrobial peptide Lynronne‐1 informs rational design of peptide with improved activity

Antibiotic resistance is a significant threat to human health, with natural products remaining the best source for new antimicrobial compounds. Antimicrobial peptides (AMPs) are natural products with great potential for clinical use as they are small, amenable to customization, and show broad‐spectr...

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Bibliographic Details
Main Authors: Jayawant, Eleanor S., Hutchinson, Jack, Gašparíková, Dorota, Lockey, Christine, Pruñonosa Lara, Lidón, Guy, Ciaran, Brooks, Rhiannon L., Dixon, Ann M.
Format: Article
Language:English
Published: Wiley, Wiley-VCH Verlag 2021
Subjects:
Online Access:https://repository.londonmet.ac.uk/9886/1/ChemBioChem%20-%202021%20-%20Jayawant%20-%20Molecular%20Basis%20of%20Selectivity%20and%20Activity%20for%20the%20Antimicrobial%20Peptide%20Lynronne%E2%80%901%20%284%29.pdf