Regulation of HIF: prolyl hydroxylases.

Regulation of HIF: prolyl hydroxylases.

Hypoxia inducible factor (HIF) is an alpha/beta heterodimeric transcriptional complex that plays a key role in directing cellular responses to hypoxia. Recent studies have defined novel oxygen-sensitive signal pathways that regulate the activity of HIF by post-translational hydroxylation at specific...

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Autors principals:	Stolze, I, Mole, D, Ratcliffe, P
Format:	Journal article
Idioma:	English
Publicat:	2006

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