Regulation of HIF: prolyl hydroxylases.

Hypoxia inducible factor (HIF) is an alpha/beta heterodimeric transcriptional complex that plays a key role in directing cellular responses to hypoxia. Recent studies have defined novel oxygen-sensitive signal pathways that regulate the activity of HIF by post-translational hydroxylation at specific...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Stolze, I, Mole, D, Ratcliffe, P
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2006