Regulation of HIF: prolyl hydroxylases.
Hypoxia inducible factor (HIF) is an alpha/beta heterodimeric transcriptional complex that plays a key role in directing cellular responses to hypoxia. Recent studies have defined novel oxygen-sensitive signal pathways that regulate the activity of HIF by post-translational hydroxylation at specific...
| Autori principali: | , , |
|---|---|
| Natura: | Journal article |
| Lingua: | English |
| Pubblicazione: |
2006
|