Regulation of HIF: prolyl hydroxylases.

Hypoxia inducible factor (HIF) is an alpha/beta heterodimeric transcriptional complex that plays a key role in directing cellular responses to hypoxia. Recent studies have defined novel oxygen-sensitive signal pathways that regulate the activity of HIF by post-translational hydroxylation at specific...

Повний опис

Бібліографічні деталі
Автори: Stolze, I, Mole, D, Ratcliffe, P
Формат: Journal article
Мова:English
Опубліковано: 2006