Lag-times between lympho-proliferative disorder and clinical diagnosis of chronic lymphocytic leukemia (CLL): a prospective analysis using plasma soluble CD23.

Background:CLL is a chronic disease that often progresses slowly from a precursor stage, monoclonal B-cell lymphocytosis (MBL), and that can remain undiagnosed for a long time. Methods:Within the European EPIC cohort, we measured pre-diagnostic plasma sCD23 for 179 individuals who eventually were di...

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Bibliographic Details
Main Authors: Kaaks, R, Sookthai, D, Luczynska, A, Oakes, C, Becker, S, Johnson, T, Johansson, A, Melin, B, Sjöberg, K, Trichopoulos, D, Trichopoulou, A, Lagiou, P, Mattiello, A, Tumino, R, Masala, G, Agnoli, C, Boeing, H, Aleksandrova, K, Brennan, P, Franceschi, S, Roulland, S, Casabonne, D, de Sanjose, S, Sanchez, M, Huerta, J
Format: Journal article
Language:English
Published: 2014