High-resolution analysis of intrahost genetic diversity in dengue virus serotype 1 infection identifies mixed infections.

High-resolution analysis of intrahost genetic diversity in dengue virus serotype 1 infection identifies mixed infections.

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Little is known about the rate at which genetic variation is generated within intrahost populations of dengue virus (DENV) and what implications this diversity has for dengue pathogenesis, disease severity, and host immunity. Previous studies of intrahost DENV variation have used a low frequency of...

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Detalhes bibliográficos
Main Authors:	Thai, K, Henn, MR, Zody, M, Tricou, V, Nguyet, N, Charlebois, P, Lennon, N, Green, L, de Vries, P, Hien, T, Farrar, J, Van Doorn, H, Jong, d, Birren, B, Holmes, E, Simmons, C
Formato:	Journal article
Idioma:	English
Publicado em:	2012

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