Whole-genome long-read TAPS deciphers DNA methylation patterns at base resolution using PacBio SMRT sequencing technology

Long-read sequencing provides valuable information on difficult-to-map genomic regions, which can complement short-read sequencing to improve genome assembly, yet limited methods are available to accurately detect DNA methylation over long distances at a whole-genome scale. By combining our recently...

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Bibliographic Details
Main Authors: Chen, J, Cheng, J, Chen, X, Inoue, M, Liu, Y, Song, C
Format: Journal article
Language:English
Published: Oxford University Press 2022