Heterogeneous genetic and non-genetic mechanisms contribute to response and resistance to azacitidine monotherapy

Acute myeloid leukaemia is prevalent in older patients that are often ineligible for intensive chemotherapy and treatment options remain limited with azacitidine being at the forefront. Azacitidine has been used in the clinic for decades, however, we still lack a complete understanding of the mechan...

Full description

Bibliographic Details
Main Authors: Symeonidou, V, Metzner, M, Usukhbayar, B, Jackson, AE, Fox, S, Craddock, CF, Vyas, P
Format: Journal article
Language:English
Published: Wiley 2022