Episodic, transient systemic acidosis delays evolution of the malignant phenotype: Possible mechanism for cancer prevention by increased physical activity

Background The transition from premalignant to invasive tumour growth is a prolonged multistep process governed by phenotypic adaptation to changing microenvironmental selection pressures. Cancer prevention strategies are required to interrupt or delay somatic evolution of the malignant invasive ph...

Full description

Bibliographic Details
Main Authors: Smallbone, K, Maini, P, Gatenby, R
Format: Journal article
Published: Biomed Central Ltd 2010