Episodic, transient systemic acidosis delays evolution of the malignant phenotype: Possible mechanism for cancer prevention by increased physical activity
Background The transition from premalignant to invasive tumour growth is a prolonged multistep process governed by phenotypic adaptation to changing microenvironmental selection pressures. Cancer prevention strategies are required to interrupt or delay somatic evolution of the malignant invasive ph...
Main Authors: | Smallbone, K, Maini, P, Gatenby, R |
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Format: | Journal article |
Published: |
Biomed Central Ltd
2010
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