Episodic, transient systemic acidosis delays evolution of the malignant phenotype: Possible mechanism for cancer prevention by increased physical activity

Background The transition from premalignant to invasive tumour growth is a prolonged multistep process governed by phenotypic adaptation to changing microenvironmental selection pressures. Cancer prevention strategies are required to interrupt or delay somatic evolution of the malignant invasive ph...

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Detalhes bibliográficos
Principais autores: Smallbone, K, Maini, P, Gatenby, R
Formato: Journal article
Publicado em: Biomed Central Ltd 2010