A genome-wide RNAi screen to dissect centriole duplication and centrosome maturation in Drosophila

Centrosomes comprise a pair of centrioles surrounded by an amorphous pericentriolar material (PCM). Here, we have performed a microscopy-based genome-wide RNA interference (RNAi) screen in Drosophila cells to identify proteins required for centriole duplication and mitotic PCM recruitment. We analys...

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Bibliographic Details
Main Authors: Dobbelaere, J, Josué, F, Suijkerbuijk, S, Baum, B, Tapon, N, Raff, J
Format: Journal article
Language:English
Published: Public Library of Science 2008