Role of IgM antibodies versus B cells in influenza virus-specific immunity.
We have compared the role of IgM antibodies with the role of B cells in control of primary influenza virus infection. Mice deficient in IgM (IgM(-/-)), but capable of producing other Igisotypes, exhibited increased pulmonary virus titers compared to wild-type mice. However, IgM(-/-) mice were less s...
Main Authors: | , , |
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Format: | Journal article |
Language: | English |
Published: |
2002
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