Role of IgM antibodies versus B cells in influenza virus-specific immunity.

We have compared the role of IgM antibodies with the role of B cells in control of primary influenza virus infection. Mice deficient in IgM (IgM(-/-)), but capable of producing other Igisotypes, exhibited increased pulmonary virus titers compared to wild-type mice. However, IgM(-/-) mice were less s...

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Bibliographic Details
Main Authors: Kopf, M, Brombacher, F, Bachmann, M
Format: Journal article
Language:English
Published: 2002