Peak and trough growth hormone (GH) concentrations influence growth and serum insulin like growth factor-1 (IGF-1) concentrations in short children.

OBJECTIVE: Growth hormone (GH) is secreted in a pulsatile fashion promoting growth and a number of diverse metabolic actions. The precise components of the pulsatile signal involved in growth regulation are unclear. DESIGN: A retrospective analysis of 24 h serum GH concentration profiles to evaluate...

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Bibliographic Details
Main Authors: Achermann, J, Brook, C, Robinson, I, Matthews, DR, Hindmarsh, P
Format: Journal article
Language:English
Published: 1999