Asymmetric syntheses of the N-terminal α-hydroxy-β-amino acid components of microginins 612, 646 and 680

The asymmetric syntheses of the N-terminal α-hydroxy-β-amino acid components of microginins 612, 646 and 680 are reported. Conjugate addition of lithium (R)-N-benzyl-N-(α-methylbenzyl)amide to the requisite (E)-α,β-unsaturated ester followed by in situ enolate oxidation with (–)-(camphorsulfonyl)oxa...

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Bibliographic Details
Main Authors: Davies, S, Fletcher, A, Hanby, A, Roberts, P, Thomson, J
Format: Journal article
Published: Elsevier 2017