Kinetic investigations of the oxygen entry pathway of the hypoxia-inducible factor (HIF) prolyl hydroxylase 2
<p>Human hypoxia inducible factor (HIF) is responsible for mediating the body’s response to low O<sub>2</sub> availability. The levels and activity of HIF are regulated by four Fe(II)/2-oxoglutarate (2OG)-dependent oxygenases, prolyl-hydroxylase domains 1-3 (PHD 1-3) and factor-inh...
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| Format: | Thesis |
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2015
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