Kinetic investigations of the oxygen entry pathway of the hypoxia-inducible factor (HIF) prolyl hydroxylase 2

<p>Human hypoxia inducible factor (HIF) is responsible for mediating the body’s response to low O<sub>2</sub> availability. The levels and activity of HIF are regulated by four Fe(II)/2-oxoglutarate (2OG)-dependent oxygenases, prolyl-hydroxylase domains 1-3 (PHD 1-3) and factor-inh...

詳細記述

書誌詳細
第一著者: Kearney, L
その他の著者: Flashman, E
フォーマット: 学位論文
出版事項: 2015