Hypoxic microenvironment shapes HIV-1 replication and latency
Viral replication is defined by the cellular microenvironment and one key factor is local oxygen tension, where hypoxia inducible factors (HIFs) regulate the cellular response to oxygen. Human immunodeficiency virus (HIV) infected cells within secondary lymphoid tissues exist in a low-oxygen or hypo...
Main Authors: | , , , , , , , , , , , , |
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格式: | Journal article |
语言: | English |
出版: |
Nature Research
2020
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