Hypoxic microenvironment shapes HIV-1 replication and latency

Hypoxic microenvironment shapes HIV-1 replication and latency

Viral replication is defined by the cellular microenvironment and one key factor is local oxygen tension, where hypoxia inducible factors (HIFs) regulate the cellular response to oxygen. Human immunodeficiency virus (HIV) infected cells within secondary lymphoid tissues exist in a low-oxygen or hypo...

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Autors principals:	Zhuang, X, Pedroza-Pacheco, I, Nawroth, I, Kliszczak, AE, Magri, A, Paes, W, Rubio, CO, Yang, H, Ashcroft, M, Mole, D, Balfe, P, Borrow, P, McKeating, JA
Format:	Journal article
Idioma:	English
Publicat:	Nature Research 2020

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