Sequence analysis reveals a conserved extension in the capping enzyme of the alphavirus supergroup, and a homologous domain in nodaviruses

<strong>Background</strong> Members of the alphavirus supergroup include human pathogens such as chikungunya virus, hepatitis E virus and rubella virus. They encode a capping enzyme with methyltransferase-guanylyltransferase (MTase-GTase) activity, which is an attractive drug target owi...

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Detalhes bibliográficos
Main Authors: Ahola, T, Karlin, D
Formato: Journal article
Idioma:English
Publicado em: BioMed Central 2015