Population pharmacokinetic modelling of primaquine exposures in lactating women and breastfed infants

Current guidelines advise against primaquine treatment for breastfeeding mothers to avoid the potential for haemolysis in infants with G6PD deficiency. To predict the haemolytic risk, the amount of drug received from the breast milk and the resulting infant drug exposure need to be characterised. He...

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Bibliographic Details
Main Authors: Wattanakul, T, Gilder, ME, McGready, R, Hanpithakpong, W, Day, NPJ, White, NJ, Nosten, F, Tarning, J, Hoglund, RM
Format: Journal article
Language:English
Published: Springer Nature 2024