Is H3K4me3 instructive for transcription activation?

Tri-methylation of lysine 4 on histone H3 (H3K4me3) is a near-universal chromatin modification at the transcription start site of active genes in eukaryotes from yeast to man and its levels reflect the amount of transcription. Because of this association, H3K4me3 is often described as an 'activ...

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Bibliographic Details
Main Authors: Howe, F, Fischl, H, Murray, S, Mellor, J
Format: Journal article
Language:English
Published: Wiley 2017