Selective deprotection strategies to N-(alpha-methylbenzyl)-beta-amino esters and derived beta lactams

A variety of N,N-diprotected β-amino esters, prepared by highly diastereoselective conjugate addition of chiral lithium amides, were selectively mono-deprotected under either reductive (hydrogenolysis) or oxidative (DDQ or CAN) conditions. Combined with these deprotection methods, lithium (α-methylb...

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書目詳細資料
Main Authors: Davies, S, Ichihara, O
格式: Journal article
語言:English
出版: 1998