Selective deprotection strategies to N-(alpha-methylbenzyl)-beta-amino esters and derived beta lactams
A variety of N,N-diprotected β-amino esters, prepared by highly diastereoselective conjugate addition of chiral lithium amides, were selectively mono-deprotected under either reductive (hydrogenolysis) or oxidative (DDQ or CAN) conditions. Combined with these deprotection methods, lithium (α-methylb...
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| Hlavní autoři: |
Davies, S,
Ichihara, O |
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| Médium: | Journal article
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| Jazyk: | English |
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| Vydáno: |
1998
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