Accuracy of loop-mediated isothermal amplification for diagnosis of human leptospirosis in Thailand.

There is a lack of diagnostic tests for leptospirosis in technology-restricted settings. We developed loop-mediated isothermal amplification (LAMP) specific for the 16S ribosomal RNA gene (rrs) of pathogenic and intermediate group Leptospira species. The lower limit of detection was 10 genomic equiv...

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Autors principals: Sonthayanon, P, Chierakul, W, Wuthiekanun, V, Thaipadungpanit, J, Kalambaheti, T, Boonsilp, S, Amornchai, P, Smythe, L, Limmathurotsakul, D, Day, N, Peacock, S
Format: Journal article
Idioma:English
Publicat: 2011