p55 and p75 tumor necrosis factor receptors are expressed and mediate common functions in synovial fibroblasts and other fibroblasts.

There is increasing evidence that TNF-alpha is a cytokine of major importance in the pathogenesis of rheumatoid arthritis. Since TNF-alpha mediates its effects via high affinity receptors, we were interested in investigating their expression and function in cells from rheumatoid tissue. Synovial fib...

Full description

Bibliographic Details
Main Authors: Butler, D, Feldmann, M, Di Padova, F, Brennan, F
Format: Journal article
Language:English
Published: 1994