p55 and p75 tumor necrosis factor receptors are expressed and mediate common functions in synovial fibroblasts and other fibroblasts.
There is increasing evidence that TNF-alpha is a cytokine of major importance in the pathogenesis of rheumatoid arthritis. Since TNF-alpha mediates its effects via high affinity receptors, we were interested in investigating their expression and function in cells from rheumatoid tissue. Synovial fib...
Prif Awduron: | Butler, D, Feldmann, M, Di Padova, F, Brennan, F |
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Fformat: | Journal article |
Iaith: | English |
Cyhoeddwyd: |
1994
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Eitemau Tebyg
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Differential regulation of tumour necrosis factor receptors (TNF-R) by IL-4; upregulation of P55 and P75 TNF-R on synovial joint mononuclear cells.
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