p55 and p75 tumor necrosis factor receptors are expressed and mediate common functions in synovial fibroblasts and other fibroblasts.
There is increasing evidence that TNF-alpha is a cytokine of major importance in the pathogenesis of rheumatoid arthritis. Since TNF-alpha mediates its effects via high affinity receptors, we were interested in investigating their expression and function in cells from rheumatoid tissue. Synovial fib...
Κύριοι συγγραφείς: | Butler, D, Feldmann, M, Di Padova, F, Brennan, F |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
1994
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Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
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The p55TNFR-IKK2-Ripk3 axis orchestrates arthritis by regulating death and inflammatory pathways in synovial fibroblasts
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